Concludes a report in the British Medical Journal.

COX-2 inhibitors may not be as secure as thought originally There is absolutely no evidence to back up claims that the new generation of anti-inflammatory drugs are less bad for the stomach lining than many traditional anti-inflammatory drugs, concludes a report in the British Medical Journal click here . These drugs were specifically designed to provide treatment without the severe gastrointestinal side effects linked to the traditional nonsteroidal anti-inflammatory drugs. Experts at the University of Nottingham determined sufferers from 367 UK general practices with an initial ever diagnosis of an upper gastrointestinal event . Each case was matched with up to 10 control patients.

Results display that almost 73 % of sleep apnea sufferers had clinically significant depressive symptoms at baseline, with an identical symptom prevalence between people. These symptoms increased progressively and independently with sleep apnea severity. However, clinically significant depressive symptoms remained in only 4 % of the sleep apnea individuals who honored CPAP therapy for three months . Of the 41 treatment adherent individuals who reported baseline feelings of self-damage or that they would be better dead, none reported persisting suicidal thoughts at the 3-month follow-up. Effective treatment of obstructive sleep apnea resulted in considerable improvement in depressive symptoms, including suicidal ideation, said senior author David R.

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